Table 4.
Eye drop at rejection (or last visit) and graft outcome after keratoplasty in all cases (N = 730).
| Characteristic | Total N = 730 |
Surgical procedure of keratoplasty | p-value1 | |||
|---|---|---|---|---|---|---|
| [A] PK N = 198 |
[B] DSAEK N = 277 |
[C] nDSAEK N = 138 |
[D] DMEK N = 117 |
|||
| Rejection episode, n (%) | 65 (8.9%) | 33 (16.7%) | 20 (7.2%) | 11 (8.0%) | 1 (0.9%) | < 0.001 |
| Follow-up period for rejection [days] | ||||||
| Mean (SD) | 1,468 (1,184) | 1,764 (1,460) | 1,126 (860) | 1,875 (1,386) | 1,295 (714) | < 0.001 |
| Median [range] | 1,138 [5, 5,758] | 1,301 [26, 5,758] | 888 [5, 5,632] | 1,728 [95, 5,198] | 1,115 [165, 3,856] | |
| Follow-up period for rejection [years] | ||||||
| Mean (SD) | 4.0 (3.2) | 4.8 (4.0) | 3.1 (2.4) | 5.1 (3.8) | 3.5 (2.0) | |
| Median [range] | 3.1 [0.0, 15.8] | 3.6 [0.1, 15.8] | 2.4 [0.0, 15.4] | 4.7 [0.3, 14.2] | 3.1 [0.5, 10.6] | |
| Eye drop usage at rejection (or last visit), n (%) | ||||||
| [1] No | 103 (14.1%) | 35 (17.7%) | 31 (11.2%) | 35 (25.4%) | 2 (1.7%) | < 0.001 |
| [2] Yes | 627 (85.9%) | 163 (82.3%) | 246 (88.8%) | 103 (74.6%) | 115 (98.3%) | |
| Eye drop breakdown, n | ||||||
| [1] Fluorometholone | 463 | 103 | 168 | 82 | 110 | |
| [2] Betamethasone | 164 | 60 | 78 | 21 | 5 | |
| Graft outcome, n (%) | ||||||
| [1] Clear | 524 (71.8%) | 111 (56.1%) | 204 (73.6%) | 101 (73.2%) | 108 (92.3%) | < 0.001 |
| [2] Recovered | 50 (6.8%) | 23 (11.6%) | 17 (6.1%) | 9 (6.5%) | 1 (0.9%) | |
| [3] Failed | 156 (21.4%) | 64 (32.3%) | 56 (20.2%) | 28 (20.3%) | 8 (6.8%) | |
DMEK descemet membrane endothelial keratoplasty, (n)DSAEK (non-)descemet’s stripping automated endothelial keratoplasty, PK penetrating keratoplasty, SD standard deviation.
Significant values are given in bold.
1Chi-square test for categorical variables; Kruskal–Wallis test for ‘Follow-up period for rejection’.