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. 2023 Feb 14;13:2635. doi: 10.1038/s41598-023-29659-w

Table 5.

Findings at rejection episode and graft outcome after the episode [Cases with rejection episode] (N = 65).

Characteristic Cases with rejection
N = 65
Surgical procedure of keratoplasty
[A] PK
N = 33
[B] DSAEK
N = 20
[C] nDSAEK
N = 11
[D] DMEK
N = 1
Time of onset from keratoplasty [days]
 Mean (SD) 641 (670) 717 (735) 507 (460) 661 (829) 629 (NA)
 Median [range] 410 [5, 3149] 438 [26, 3149] 284 [5, 1408] 362 [132, 2994] 629 [629, 629]
Eye drop, n (%)
 [1] No 8 (12.3%) 1 (3.0%) 4 (20.0%) 3 (27.3%) 0 (0.0%)
 [2] Fluorometholone 32 (49.2%) 14 (42.4%) 11 (55.0%) 6 (54.5%) 1 (100.0%)
 [3] Betamethasone 25 (38.5%) 18 (54.5%) 5 (25.0%) 2 (18.2%) 0 (0.0%)
Suture related event, n (%) 12 (18.5%) 8 (24.2%) 3 (15.0%) 1 (9.1%) 0 (0.0%)
Symptomatic case, n (%) 33 (50.8%) 17 (51.5%) 8 (40.0%) 7 (63.6%) 1 (100.0%)
Conjunctival hyperemia, n (%) 17 (26.2%) 9 (27.3%) 6 (30.0%) 2 (18.2%) 0 (0.0%)
Corneal edema, n (%) 30 (46.2%) 15 (45.5%) 9 (45.0%) 5 (45.5%) 1 (100.0%)
Keratic precipitate, n (%) 58 (89.2%) 28 (84.8%) 19 (95.0%) 10 (90.9%) 1 (100.0%)
Vascularization of cornea, n (%) 13 (20.0%) 9 (27.3%) 3 (15.0%) 1 (9.1%) 0 (0.0%)
Peripheral anterior synechia, n (%) 9 (13.8%) 4 (12.1%) 4 (20.0%) 1 (9.1%) 0 (0.0%)
Rejection line, n (%) 4 (6.2%) 4 (12.1%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
Graft outcome, n (%)
 [1] Recovered 50 (76.9%) 23 (69.7%) 17 (85.0%) 9 (81.8%) 1 (100.0%)
 [2] Failed 15 (23.1%) 10 (30.3%) 3 (15.0%) 2 (18.2%) 0 (0.0%)

DMEK descemet membrane endothelial keratoplasty, (n)DSAEK (non-)descemet’s stripping automated endothelial keratoplasty, PK penetrating keratoplasty, SD standard deviation.