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. 2023 Jan 3;10(5):2204443. doi: 10.1002/advs.202204443

Figure 5.

Figure 5

In vivo efficacy testing using a neutropenic thigh‐infection model in mice. A) Schematic overview of the experimental layout depicting groups and treatment regimens. B) Bacterial burden detected in the primary infection site (muscle). C) Bacterial burden detected in the secondary infection site (lung). **** p < 0.0001, *** p < 0.001, ** p < 0.01. (CFU: colony‐forming unit; p.i.: post infection; IP: intraperitoneal; SC: subcutaneous; IV: intravenous; QSI: quorum sensing inhibitor; TOB: tobramycin).