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. 2023 Jan 25;21:1324–1348. doi: 10.1016/j.csbj.2023.01.028

Table 2.

Confidence score thresholds for two classes of protein–protein interactions.

Classes Confidence Score Description
class 1 0 ≥ – ≤ 0.5 The score threshold is assigned to non-interacting protein pairs.
A score of zero suggests a non-interactive pair with the highest confidence
class 2 > 0.5 – ≤ 1 This range indicates interacting protein pairs based on experimental and theoretical evidence.
A score of one indicates full confidence in the protein pair’s interactivity.