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. 2023 Jan 25;21:1324–1348. doi: 10.1016/j.csbj.2023.01.028

Table 3.

Confidence score thresholds for three classes of protein–protein interactions.

Classes Confidence Score Description
class 1 0 ≥ – ≤ 0.4 The interaction confidence threshold is low.
class 2 > 0.4 – ≤ 0.7 A score in this range may indicate a falsely labelled pair.(for instance, a score of 0.5 suggests that nearly every second interaction may be incorrectly labelled as an interacting pair).
class 3 > 0.7 – ≤ 1 This range shows highly interactive protein pairs based on experimental and theoretical evidence. A score of one indicates full confidence in the protein pair’s interactivity.