Table 1.
Demographic description of the sample according to diagnostic group.
| Controls (n = 7) | AD-MCI (n = 7) | AD-D (n = 7) | ||
|---|---|---|---|---|
| Age | Mean ± SD | 71 ± 12.3 | 63.8 ± 9.3 | 64.4 ± 10.3 |
| Range | 53–88.6 | 53.7–81 | 53.9–82.7 | |
| Sex | Female | 3 (43%) | 3 (43%) | 7 (100%) |
| Male | 4 (57%) | 4 (57%) | 0 (0%) | |
| APOE | E3/E3 | 7 (100%) | 1 (14%) | 1 (14%) |
| E3/E4 | 0 (0%) | 5 (72%) | 3 (43%) | |
| E4/E4 | 0 (0%) | 1 (14%) | 3 (43%) | |
| PiB GCI | Median | 1.42 (1.19–3.1) | 2.87 (2.38–3.44) | 2.94 (2.37–4.16) |
| CDR SOB (/18) | Median | 0.0 (0.0–1.0) | 4.5 (3.0–6.0) | 11.0 (7.0–15.0) |
| MMSE (/30) | Median | 29.0 (25.0–30.0) | 23.0 (14.0–27.0) | 8.0 (5.0–23.0) |
| CSF tau (pg/ml) | Mean | NA | 651.4 ± 291.5 | 591.6 ± 283.3 |
| Range | NA | 349–1200 | 265–947 | |
| CSF ptau (pg/ml) | Mean | NA | 82.57 ± 22.6 | 71.29 ± 26.3 |
| Range | NA | 55–119 | 38–104 | |
| Ab 42 CSF (pg/ml) | Mean | NA | 437.9 ± 98.6 | 433.1 ± 86.9 |
| Range | NA | 299–538 | 323–558 | |