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. 2023 Feb 14;13:2623. doi: 10.1038/s41598-023-29721-7

Table 3.

Covariance analysis of FVC%, FEV1%, FEV1/FVC% in different PPD-exposure group (mean ± SD).

Variable Lower exposure (n = 24) Middle exposure (n = 50) Higher exposure (n = 50) F P value
FVC% 103.044 ± 9.498 89.076 ± 11.806*# 101.399 ± 9.409 7.519  < 0.001
FEV1% 104.665 ± 12.289 91.772 ± 6.261* 92.483 ± 10.300* 8.791  < 0.001
FEV1/FVC% 102.215 ± 14.040 104.700 ± 14.779# 91.889 ± 12.737* 6.855  < 0.001

Measurement indexes of capacity and the volume of lung include forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and ratio of FEV1 to FVC (FEV1/FVC), etc. Abnormal pulmonary function is defined as: FVC% (percentage of forced vital capacity, FVC measured value/FVC predicted value) < 80%; FEV1% (percentage of forced expiratory volume in 1 s, FEV1 measured value/FEV1 predicted value) < 75%; FEV1/FVC%, FEV1 measured value/FVC measured value < 70%. The predictive values of FVC or FEV1 is automatically calculated by the pulmonary function analyzer according to age, gender, height, weight and race.

*P < 0.05, comparison of the higher and middle exposure group with the lower exposure group by Bonferroni method.

#P < 0.05, comparison between the higher exposure group and middle exposure group by Bonferroni method.

The covariant variables including gender, ethnic group, working age, education condition and recent hair dye history.