Table 2. Brain network graph measures in acute mTBI patients and healthy controls.
| Graph measures | mTBI (n=71) | HC (n=57) | P value | Cohen’s d |
|---|---|---|---|---|
| Functional network | ||||
| Gamma | 0.75±0.14 | 0.34±0.01 | <0.001* | 4.076 |
| Lambda | 0.49±0.01 | 0.49±0.02 | 0.14 | −0.257 |
| Sigma | 0.68±0.13 | 0.65±0.13 | 0.19 | 0.231 |
| Cp | 0.27±0.01 | 0.27±0.01 | 0.42 | 0.160 |
| Lp | 0.86±0.07 | 0.87±0.07 | 0.59 | −0.091 |
| Eg | 0.26±0.01 | 0.25±0.01 | 0.75 | 0.095 |
| Eloc | 0.34±0.01 | 0.34±0.01 | 0.35 | 0.235 |
| Structural network | ||||
| Gamma | 1.57±0.28 | 1.48±0.14 | 0.03* | 0.390 |
| Lambda | 0.50±0.01 | 0.50±0.01 | 0.14 | 0.248 |
| Sigma | 1.41±0.22 | 1.34±0.11 | 0.03* | 0.395 |
| Cp | 0.19±0.01 | 0.19±0.01 | 0.11 | −0.266 |
| Lp | 1.07±0.06 | 1.06±0.39 | 0.10 | 0.053 |
| Eg | 0.19±0.01 | 0.19±0.01 | 0.13 | −0.232 |
| Eloc | 0.28±0.01 | 0.29±0.01 | 0.09 | −0.300 |
| Functional-structural coupling | ||||
| Coupling | 0.22±0.04 | 0.20±0.03 | 0.02* | 0.415 |
Data are presented as mean ± standard deviation. The AUC across the full range of sparsity thresholds was calculated for graph measures of functional and structural network. * denotes significant difference compared to HC, Bonferroni-corrected P<0.05. mTBI, mild traumatic brain injury; HC, healthy controls; Cp, clustering coefficient; Lp, characteristic path length; Eg, global efficiency; Eloc, local efficiency; AUC, area under the curve.