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. 2023 Jan 30;21:65–73. doi: 10.1016/j.ijpddr.2023.01.003

Fig. 6.

Fig. 6

Kaplan-Meier curves of CIDD-72229 killing of Schistosoma mansoni. CIDD-72229 was tested in adult male worms at final concentrations of 143 μM, 71.5 μM, 35.75 μM, and 14.3 μM per well in vitro. Worms were challenged with CIDD-72229 for 45 min, followed by thorough washing to remove the drug. Survival was monitored for 14 days. All screens were performed in experimental and biological triplicate. Survival was plotted as a percentage over time using Prism/Curve Comparison/Long-rank (Mantel-cox) test. The p-value threshold for each CIDD-72229 compared to DMSO was <0.001.