Table 2.
Inflammatory cytokine character and alteration in the burn model.
| Cytokines | Character | Sample | Site | Upregulation or downregulation | Refs. |
|---|---|---|---|---|---|
| IL-1β | Pro-inflammatory factor | Human/Mouse | Plasma | Up | (81, 82) |
| IL-4 | Anti-inflammatory factor | Human | Plasma | Down | (84) |
| IL-6 | Pro-inflammatory factor | Human/Mouse Mouse |
Plasma Wound |
Up Up Down |
(81–89) (90) (91) |
| IL-7 | Pro-inflammatory factor | Human | Plasma | Down | (84) |
| IL-8 | Pro-inflammatory factor | Human | Plasma | Up | (83–89) |
| IL-10 | Anti-inflammatory factor | Human | Plasma | UP | (8, 83, 87–89) |
| G-CSF | Pro-inflammatory factor | Human | Plasma | Up | (85–87) |
| GM-CSF | Pro-inflammatory factor | Human | Plasma | Up | (85) |
| MIP-1 | Pro-inflammatory factor | Human Mouse |
Plasma Wound |
Up Up |
(83–86, 89) (90) |
| TNF-α | Pro-inflammatory factor | Human Mouse |
Plasma Wound |
Up Up Down |
(87, 88) (90) (91) |