Table 3.

Experiments that shift the appetite or diet lines and show the predicted overshoot or undershoot in food intake

Intervention	Line affected	Overshoot	Reference
cold temperature	Diet	no	Cottle and Carlson, Hamilton and Brobeck33,34
Exercise	Diet	no	Mazzeo and Horvath8
Hyperthyroidism	Diet	no	Ishii et al., 20035; Luo and MacLean, 20037; Mazzeo et al., 19868
Leptin pathway inhibition	Appetite	overshoot	Fox et al., 200712; Zhang et al., 200716; Rushing et al., 200114
Leptin pathway activation	Appetite	undershoot	Fox et al., 200712; Roth et al., 200645
Satiety-inducing nutrients	Appetite	undershoot	Adam et al., Zhou et al., Fantini et al.46,48,54