Table 5.
Whole-brain and region of interest (ROI) effects of attention-deficit hyperactivity disorder (ADHD) traits on brain activation during reward anticipation and deliverya
| Effect of ADHD rating scale | Interaction ADHD rating scale × diagnosis | |
|---|---|---|
| Anticipation | ||
| Whole brain | All F < 20.89, PFWE > 0.05 | All F < 20.90, PFWE > 0.05 |
| ROI | Left ventral striatum: F(1,317) = 0.668, P = 0.414, partial η2 = 0.002 Right ventral striatum: F(1,317) = 1.136, P = 0.287, partial η2 = 0.004 |
Left ventral striatum: F(1,328) = 0.129, P = 0.722, partial η2 = 0.000 Right ventral striatum: F(1,328) = 0.570, P = 0.451, partial η2 = 0.002 |
| Delivery | ||
| Whole brain | All F < 21.39, PFWE > 0.05 | All F < 21.42, PFWE > 0.05 |
| ROI | Left ventral striatum: F(1,307) = 0.143, P = 0.705, partial η2 = 0.000 Right ventral striatum: F(1,307) = 0.062, P = 0.804, partial η2 = 0.000 |
Left ventral striatum: F(1,307) = .068, P = 0.795, partial η2 = 0.000 Right ventral striatum: F(1,307) = 0.664, P = 0.416, partial η2 = 0.002 |
Table provides test statistic for whole brain and ROI analysis for ADHD traits. Voxel-level statistics were family-wise error (FWE) corrected for the number of voxels across the whole brain for each test. Significance was defined as PFWE < 0.05 with a cluster threshold of k ≥ 5. For ROI analysis in the left and right ventral striatum, the critical alpha level was adjusted to P < 0.025 to control for multiple comparisons. Small effect sizes correspond to partial η2 > 0.00995, medium effect sizes correspond to partial η2 > 0.0588 and large effect sizes correspond to partial η2 > 0.1379.