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. 2023 Feb 15;8:19. doi: 10.1038/s41541-023-00620-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — IFNγ secreting spot forming cells (SFC) were enumerated following stimulation with a pool of peptides covering NP (a), NA2 (b) and M1 (c) proteins or pH1N1 (d) and H3N2 (e) viruses. The arrows below D28 and D56 indicate the immunizations with ChAdOx-NPM1-NA2 and MVA-NPM1-NA2. Each symbol represents an individual animal, the top of the bar the mean and the line the standard error (SEM). Asterisks denote significance between indicated groups (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001). The data were analyzed by two-way ANOVA and Bonferroni’s multiple comparisons test.