Fig. 1.

PRISMA flowchart of publications included in the SLR. *SLRs and cost-effectiveness models captured in the database search that met inclusion criteria underwent a manual bibliography check, and data was extracted from studies that met inclusion criteria and were not already captured. ^†Search was designed to capture studies reporting the clinical, humanistic, and economic burdens of influenza. For this publication only studies reporting relevant clinical outcomes were included. CEM cost-effectiveness model, PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses, SLR systematic literature review