Table 3:
Risk ratio estimates for low birthweight by paternal PBB/PCB tertiles, dichotomized at 25th percentile for birthweight (<3232 grams)
| PBB exposure level (range in ppb) (n=below/above cut point and total) |
Unadjusted RR (95% CI) for birthweight <3232 grams1 |
Adjusted RR (95% CI) for birthweight <3232 grams2 |
Adjusted RR (95% CI) for birthweight <3232 grams including BMI4 |
|---|---|---|---|
| PBB Tertile 1 (<LOD-3.0) (n=23/97, 120) | 1.00 (referent) | 1.00 (referent) | 1.00 (referent) |
| PBB Tertile 2 (4.0-8.0) (n=28/70, 98) | 1.62 (0.86, 3.03) | 1.67 (0.93, 2.99) * | 1.50 (0.86, 2.65) |
| PBB Tertile 3 (9.0-1744.0) (n=38/80, 118) | 1.76 (1.00, 3.10) ** | 2.06 (1.12, 3.79) ** | 1.69 (0.94, 3.05) * |
| PCB exposure level (range in ppb) (n=below/above cut point and total) |
Unadjusted RR (95% CI) for birthweight <3232 grams1 |
Adjusted RR (95% CI) for birthweight <3232 grams3 |
Adjusted RR (95% CI) for birthweight <3232 grams including BMI5 |
| PCB Tertile 1 (<LOD-5.0) (n=19/72, 91) | 1.00 (referent) | 1.00 (referent) | 1.00 (referent) |
| PCB Tertile 2 (6.0-8.0) (n=34/74, 108) | 1.73 (0.94, 3.18) * | 1.47 (0.79, 2.75) | 1.24 (0.68, 2.25) |
| PCB Tertile 3 (9.0-85.0) (n=29/68, 97) | 1.68 (0.92, 3.09) * | 1.34 (0.70, 2.54) | 1.21 (0.66, 2.24) |
RR=risk ratio, CI=confidence interval
Model adjusted for offspring born to the same father
Model adjusted for offspring born to the same father, maternal PBB concentration, offspring gestational age and sex, paternal age at offspring birth, paternal age at PBB exposure, and paternal education
Model adjusted for offspring born to the same father, maternal PCB concentration, offspring gestational age and sex, paternal age at offspring birth, and paternal education
Sensitivity analysis adjusted for offspring born to the same father, maternal PBB concentration, offspring gestational age and sex, paternal age at offspring birth, paternal age at PBB exposure, paternal education, and paternal BMI
Sensitivity analysis adjusted for offspring born to the same father, maternal PCB concentration, offspring gestational age and sex, paternal age at offspring birth, paternal education, and paternal BMI
p<0.1
p<0.05