Table 2.
Top 15 features ranked by the average ranking of feature importance and absolute feature weight of lasso regression
| Male | Female | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Feature | IRFa | RIRFb | AFWLc | RAFWLd | ARe | P | Feature | IRF | RIRF | AFWL | RAFWL | AR | P |
| 6-m walk | 0.1987 | 1 | 1.1335 | 1 | 1 | < 0.001 | HGS | 0.1440 | 1 | 1.1379 | 1 | 1 | < 0.001 |
| HGS | 0.1470 | 2 | 1.0320 | 2 | 2 | < 0.001 | 6-m walk | 0.1233 | 2 | 0.6048 | 2 | 2 | < 0.001 |
| age | 0.0600 | 3 | 0.5118 | 3 | 3 | < 0.001 | AWVA | 0.0241 | 3 | 0.4042 | 3 | 3 | < 0.001 |
| FBG | 0.0236 | 4 | 0 | 9 | 6.5 | 0.007 | TBIL | 0.0229 | 4 | 0 | 9 | 6.5 | 0.048 |
| PTH | 0.0220 | 5 | 0 | 9 | 7 | 0.001 | TP | 0.0186 | 5 | 0 | 9 | 7 | 0.23 |
| pre-CRE | 0.0217 | 6 | 0 | 9 | 7.5 | < 0.001 | TG | 0.0177 | 6 | 0 | 9 | 7.5 | 0.459 |
| AG | 0.0197 | 7 | 0 | 9 | 8 | 0.192 | AST/ALT | 0.0169 | 7 | 0 | 9 | 8 | 0.125 |
| post-CRE | 0.0188 | 8 | 0 | 9 | 8.5 | < 0.001 | SMI | 0.0154 | 8 | 0 | 9 | 8.5 | 0.004 |
| AST | 0.0137 | 10 | 0 | 9 | 9.5 | 0.002 | CysC | 0.0144 | 9 | 0 | 9 | 9 | 0.142 |
| LY% | 0.0125 | 11 | 0 | 9 | 10 | 0.063 | WC | 0.0140 | 10 | 0 | 9 | 9.5 | 0.098 |
| TP | 0.0115 | 12 | 0 | 9 | 10.5 | 0.33 | post-CRE | 0.0134 | 11 | 0 | 9 | 10 | 0.009 |
| RDW-CV | 0.0110 | 13 | 0 | 9 | 11 | 0.21 | age | 0.0132 | 12 | 0 | 9 | 10.5 | 0.001 |
| CysC | 0.0107 | 14 | 0 | 9 | 11.5 | 0.454 | s-Fe | 0.0129 | 13 | 0 | 9 | 11 | 0.244 |
| height | 0.0105 | 15 | 0 | 9 | 12 | 0.017 | weight | 0.0127 | 14 | 0 | 9 | 11.5 | 0.107 |
| s-Mg | 0.0103 | 16 | 0 | 9 | 12.5 | 0.478 | pre-CRE | 0.0126 | 15 | 0 | 9 | 12 | 0.01 |
HGS Handgrip strength, FBG Fasting blood glucose, PTH Parathyroid hormone, pre-CRE Pre-dialysis creatinine, AG Anion gap, post-CRE Post-dialysis creatinine, AST Aspartate aminotransferase, LY% Lymphocyte percentage, TP Total protein, RDW-CV Red blood cell distribution width—coefficient of variation, CysC Cystatin C, s-Mg Serum magnesium, AWVA Arm without vascular access, WC Waist circumference, TBIL Total bilirubin, TG Triglyceride, AST/ALT Aspartate aminotransferase/alanine aminotransferase, SMI Skeletal muscle index, s-Fe Serum ferritin
aImportance value calculated by RF
bRanking of importance value calculated by RF
cAbsolute feature weight of lasso regression
dRanking of absolute feature weight of lasso regression
eAverage ranking