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. 2023 Feb 2;27(4):538–552. doi: 10.1111/jcmm.17678

FIGURE 6.

FIGURE 6

Correlation analysis of VEGFA expression and infiltration levels of immune cells in tumour tissues. (A) VEGFA expression was positively correlated with tumour purity and infiltration levels of B cells, CD8+ T cells, CD4+ T cells, macrophages and DCs in HCC tissues based on the TIMER database. (B–D) The relationship between VEGFA mRNA expression and CD8+ T cells, CD4+ T cells and regulatory T cells in various tumours was evaluated using a variety of algorithms based on the TIMER database. (E) Correlation between VEGFA expression level and infiltration of various immune cells (Th2 Cell, T helper Cell, Eosinophils, TFH, Tcm, NK CD58bright Cell, Th17‐cell, sDC, CD8+ T‐cell, Th1‐Cell, Macrophages, NK‐Cell, Treg, Tem, Mast cell, NK CD58dim Cell, B‐cell, iDC, Neutrophils, T‐cell, Tgd, pDC, Cytotoxic Cell, DC) in HCC tissues. (F–H) Correlation between VEGFA expression level and PDCD1, CTLA4 and CD86 expression levels in HCC tissues based on TCGA database. (I) The correlation between VEGFA expression levels and PDCD1, CTLA4 and CD86 expression levels in HCC tissues was detected by immunofluorescence