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. 2023 Feb 1;15:1055433. doi: 10.3389/fnagi.2023.1055433

Figure 9.

Figure 9

Regional differences in node strength. Regional differences in node strength following chronic placebo, CBD, or Δ9-THC over 28 days (chronic) and after a 2-week washout period (lasting). (A) Connectome maps of a mouse functional network highlighting mean node strength across groups. Spheres represent scaled area under the curve (AUC) values for node strength calculated over several edge density thresholds (2–40%). Size and color intensity of spheres reflect high-to-low values (see scale bar). Lines between nodes represent pairwise connectivity between nodes (these are shown at edge density of 6% for visual clarity). (B) Node strength values for chronic treatment mice (calculated at a 16% edge density threshold). (C) Node strength values for post-washout period (calculated at a 16% edge density threshold). Data are shown as mean ± standard error (t-test, FDR q = 0.05, p < 0.01). Abbreviations: L VISPM, left posteromedial visual cortex; L AUDP, left posterior auditory cortex; L AUDV, left ventral auditory cortex; L VISAA, left anterior area of the visual cortex; L VISPV1, left ventroposterior visual cortex node 1; L SCC1, primary somatosensory cortex; R PAINS1, right posterior agranular insula node 1.