Table 2.

Hematological Assessment of Leukocytes in CD-1 Mice

	sham	alum/PncO			LEPS(20V)/CRM197
blood cell	–	1×	5×	10×	1×	5×	10×
Male CD-1 Mice (N = 5)
basophiles	0.1 ± 0.1	0.1 ± 0.1	0.1 ± 0.1	0.1 ± 0.1	0.1 ± 0.1	0.1 ± 0.1	0.1 ± 0.1
eosinophiles	3.1 ± 2.2	3.2 ± 2.0	2.8 ± 2.1	2.9 ± 2.2	2.9 ± 2.5	3.1 ± 2.5	3.0 ± 2.5
lymphocytes	79.1 ± 5.8	80.8 ± 2.7	81.4 ± 2.4	82.4 ± 3.8	80.4 ± 1.4	80.7 ± 3.4	82.3 ± 4.0
monocytes	8.7 ± 5.4	8.0 ± 5.2	8.3 ± 5.6	7.4 ± 2.5	8.5 ± 4.4	8.3 ± 4.1	7.8 ± 6.2
neutrophiles	8.0 ± 2.9	8.0 ± 3.3	7.3 ± 2.5	7.2 ± 2.3	8.4 ± 3.0	7.8 ± 3.4	7.3 ± 3.5
erythrocytes	7.5 ± 0.3	7.2 ± 0.3	7.1 ± 0.2	7.9 ± 0.3	7.9 ± 0.3	7.7 ± 0.2	7.4 ± 0.2
leukocytes	6.1 ± 1.3	6.7 ± 1.1	6.8 ± 1.0	6.5 ± 1.2	6.1 ± 1.0	6.2 ± 1.3	6.9 ± 1.0
thrombocytes	1100.0 ± 150.0	1122.0 ± 160.5	1089.0 ± 126.0	1056.0 ± 153.0	1155.0 ± 124.5	1078.0 ± 156.0	1100.0 ± 147.0
Female CD-1 Mice (N = 5)
basophiles	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
eosinophiles	5.1 ± 2.3	5.3 ± 2.8	5.3 ± 2.5	5.4 ± 2.7	5.3 ± 1.9	5.2 ± 2.3	5.3 ± 2.8
lymphocytes	75.4 ± 5.1	78.2 ± 4.7	80.7 ± 5.0	78.9 ± 5.4	80.7 ± 3.9	76.2 ± 4.1	79.9 ± 6.2
monocytes	6.5 ± 2.7	6.6 ± 3.2	6.0 ± 2.1	6.7 ± 3.1	6.6 ± 2.8	6.4 ± 3.2	6.4 ± 3.1
neutrophiles	13.1 ± 4.3	10.0 ± 4.2	8.1 ± 4.0	9.2 ± 3.5	7.9 ± 4.1	12.6 ± 5.2	9.1 ± 4.2
erythrocytes	8.1 ± 0.3	8.1 ± 0.2	8.1 ± 0.2	7.9 ± 0.2	7.7 ± 0.3	8.5 ± 0.2	8.3 ± 0.3
leukocytes	4.2 ± 0.9	4.5 ± 0.7	4.5 ± 1.0	4.7 ± 1.0	4.5 ± 0.9	4.4 ± 0.7	4.2 ± 0.9
thrombocytes	936.0 ± 225.0	964.1 ± 265.5	982.8 ± 258.8	907.9 ± 229.5	973.4 ± 200.2	898.6 ± 177.8	945.4 ± 240.8