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. 2022 Apr 3;33(4):1310–1327. doi: 10.1093/cercor/bhac137

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Fig. 8 — The association between cognitive decline and hippocampal volume from aMCI to AD. (A) the quadratic cognitive decline trajectories as a function of time to AD conversion. A linear mixed-effects model was used to estimate the quadratic changes of cognitive functions as a function of time to AD conversion. (B) The quadratic association between hippocampal volume and cognitive functions. Abbreviations: ADAS13 = Alzheimer’s Disease Assessment Scale Cognitive-13; CDRSB = Clinical Dementia Rating Scale Sum of Boxes; lHip = left hippocampus; m = month; MMSE = Mini-Mental State Examination; RAVLTimm = Rey Auditory Verbal Learning Test immediate recall; rHip = right hippocampus.