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. 2022 Mar 25;33(4):917–932. doi: 10.1093/cercor/bhac110

Table 2.

Treatment-mediated changes in PDRP network metrics.

Interventiona (number of subjects) Assortativity coefficient Degree centrality Clustering coefficient Characteristic path length Small-worldness
Levodopa infusion (14) (“on” vs. “off” medication) Inline graphic 0 0 Inline graphic Inline graphic
STN AAV2-GAD (16) (12 months vs. baseline) Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic
Sham surgery (21) (12 months vs. baseline) Inline graphic 0 Inline graphic 0 0

Increase: Inline graphic and Inline graphic = P < 0.05 and P < 0.001 versus baseline (see text), for comparison of treatment with baseline.

Decrease: Inline graphic and Inline graphic = P < 0.05 and P < 0.001 versus baseline (see text), for comparison of treatment with baseline.

No change = 0.