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. Author manuscript; available in PMC: 2023 Jul 4.
Published in final edited form as: Nature. 2023 Jan 4;613(7943):383–390. doi: 10.1038/s41586-022-05565-5

Extended Data Fig. 7: Sequence alignment of METTL1 protein homologs.

Extended Data Fig. 7:

Sequences used are from human (Q9UBP6), Mus musculus (Q9Z120), Bos taurus (Q2YDF1), Xenopus laevis (Q6NU94), Danio rerio (Q5XJ57), Drosophila melanogaster (O77263), Caenorhabditis elegans (Q23126) and Saccharomyces cerevisiae (Q12009) METTL1. Sequences were aligned using Clustal Omega and visualized by Geneious Prime. Residues within 4 Å of RNA in different states are indicated with asterisks.