Table 1.

Eligibility criteria for population/participants, intervention/exposure, control, outcome, timeframe, study design and settings (PI/ECOTSS)

Population	Intervention or Exposure	Comparators	Outcomes	Timing	Setting	Study design
Adults, general population	Nuts and seeds intake, including peanuts	Dose-response (per serving/day) or high versus low or no intake	Fatal or non-fatal atherosclerotic cardiovascular disease (including coronary artery disease, myocardial infarction, ischemic stroke, CVD mortality), type 2 diabetes incidence and mortality. RCTs only: Changes in atherogenic serum lipids, blood pressure, fasting glycaemia (glucose, HbA1c), insulin and insulin resistance/insulin sensitivity.	Minimum 12 months follow-up in cohort studies. Minimum 12-week intervention in intervention studies.	Relevant for the general population in the Nordic and Baltic countries. Not weight-loss studies.	RCTs (for risk factors), prospective cohort studies