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. 2023 Feb 14;55(1):615–623. doi: 10.1080/07853890.2023.2178669

Table 3.

ECG and echocardiographic changes before and in a mean follow-up of 10 months after percutaneous ASD closure.

  Baseline Post Mean of the difference
(95% CI)
p-value
AF on ECG: 6.21% (55) 7.59% (34) −1.4% (−4.3% to 1.5%) .267
RBBB or pRBBB on ECG 49.2% (384) 18.9% (82) 30.3% (25.2% to 35.4%) <.001
LV EF 64.2 (8.85) 65.2 (7.25) −0.96 (−0.21 to −1.71) .012
TAPSE 25.9 (6.02) 23.7 (5.12) 2.38 (0.71 to 4.05) .0058
ASD flow on TTE 85.4% (677) 8.87% (59) 76.5% (73.2% to 79.8%) <.001
Aortic regurgitation        
 Mild 6.22% (55) 6.75% (41) −0.5% (−3.1% to 2.0%) .68
 Moderate 0.57% (5) 0.82% (5) −0.3% (−1.1% to 0.6%) .55
 Severe 0.0% (0) 0.0% (0) NA NA
Mitral regurgitation        
 Mild 18.6% (165) 25.3% (154) −6.7% (−11% to −2.4%) .002
 Moderate 2.47% (22) 2.30% (14) 0.2% (−1.4% to 1.7%) .83
 Severe 0.11% (1) 0.00% (0) 0.1% (−0.1% to 0.3%) .41
Tricuspid regurgitation        
 Mild 52.1% (440) 58.7% (341) −7.5% (−12.7% to −2.3%) .005
 Moderate 8.10% (70) 4.79% (28) 3.3% (0.8% to 5.8%) .014
 Severe 1.16% (10) 0.68% (4) 0.5% (−0.5% to 1.4%) .37
 TI gradient 30.3 (11.5) 25.2 (9.55) 5.59 (4.22 to 6.96) <.001
 Enlarged right side 83.9% (745) 24.4% (138) 59.5% (55.2% to 63.8%) <.001
 RV size (RV + RA area) 45.5 (13.5) 34.6 (11.4) 13.16 (10.07 to 16.24) <.001

AF: Atrial fibrillation; ASD: atrial septal defect; LV EF: Left ventricular ejection fraction; NA: Not applicable; pRBBB: Partial right bundle branch block; RA: Right atrium; RBBB: Right bundle branch block; RV: Right ventricle; TAPSE: Tricuspid annular plane systolic excursion; TI: Tricuspid valve insufficiency; TIA: Transient ischemic attack; VF: Ventricular fibrillation; VT: Ventricular tachycardia.

Values are presented as mean (SD) for continuous variables or percentage (number of patients) for categorical variables.