Table 3.
Drug | 1-year lag analysis | 3-year lag analysis | ||||||||
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% exposed | % exposed | |||||||||
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Cases | Controls | OR | Std Error | p-value | Cases | Controls | OR | Std Error | p-value | |
Women | ||||||||||
Estrogens, conjugated | 8.09 | 5.94 | 1.16 | 0.05 | 0.007 | 6.17 | 5.10 | 0.99 | 0.07 | 0.90 |
Estradiol | 5.53 | 4.32 | 1.01 | 0.065 | 0.851 | 4.06 | 3.24 | 0.94 | 0.09 | 0.49 |
Estradiol/levonorgestrel | – | – | 0.42 | 1.03 | 0.407 | 0.69 | 0.14 | 0.58 | 1.05 | 0.60 |
Estradiol/norethindrone | – | – | 0.68 | 0.37 | 0.293 | – | – | 0.83 | 0.43 | 0.66 |
Estrogen,con/m-progest | 0.67 | 0.67 | 0.85 | 0.18 | 0.355 | 0.52 | 0.55 | 0.77 | 0.26 | 0.23 |
Raloxifene | 3.60 | 3.42 | 0.94 | 0.08 | 0.447 | 3.16 | 2.96 | 0.91 | 0.10 | 0.33 |
Tamoxifen | 0.56 | 0.75 | 0.62 | 0.19 | 0.011 | 0.45 | 0.59 | 0.61 | 0.25 | 0.04 |
Testosterone | – | – | 3.93 | 0.45 | 0.002 | – | – | 4.92 | 0.54 | 0.003 |
Men | – | – | – | – | – | – | – | – | – | – |
Testosterone | 2.22 | 1.41 | 1.27 | 0.10 | 0.027 | 1.29 | 0.90 | 1.12 | 0.15 | 0.47 |
Tamoxifen | – | – | 1.65 | 0.65 | 0.442 | – | – | – | – | – |
Estrogens, conjugated | – | – | 1.48 | 0.78 | 0.616 | – | – | – | – | – |