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. 2023 Feb 13;9:e43730. doi: 10.2196/43730

Table 4.

Effect size of digital mental health services for reducing anxiety symptoms during the COVID-19 pandemic according to study characteristics.

Group Studies, n SMDa (95% CI) Q P value
Sample size 0.24 .62

≥81 7 −0.54 (−1.01 to −0.07)


<81 8 −0.85 (−1.99 to 0.29)

Location 0.49 .48

High-income countries 10 −0.49 (−0.66 to −0.13)


LMICsb 5 −1.17 (−3.02 to 0.68)

Measurement of anxiety1 0 .95

GAD-7c 5 −0.68 (−1.31 to −0.04)


Other measurementsd 10 −0.71 (−1.61 to 0.19)

Measurement of anxiety2 2.06 .15

DASS-21e 4 −0.23 (−0.38 to −0.08)


Other measurements 11 −0.85 (−1.68 to −0.02)

Duration of follow-up 1.14 .29

Short-term 12 −0.80 (−1.55 to −0.06)


Long-term 3 −0.29 (−0.86 to 0.29)

Duration of intervention 0.58 .45

≥4 weeks 9 −0.47 (−0.91 to −0.04)


<4 weeks 6 −1.07 (−2.56 to 0.41)

a SMD: standardized mean difference.

bLMICs: low- and middle-income countries.

cGAD-7: Generalized Anxiety Disorder-7.

dOther measurements including Beck Anxiety Inventory, Brief Symptom Inventory, Child Behavior Checklist, College Counseling Center Assessment of Psychological Symptoms, Hamilton Anxiety Rating Scale, Self-rating Anxiety Scale, and State-Trait Anxiety Inventory.

eDASS−21: Depression Anxiety Stress Scales-21.