Table 3.
Effect of UPPs on serum biochemical parameters in high-fat diet-fed C57BL/6 mice.
| Item | Control | HFD | UPPL | UPPM | UPPH |
|---|---|---|---|---|---|
| AST (U/L) | 95.4 ± 32.6a | 99.3 ± 26.0a | 95.0 ± 38.8a | 83.0 ± 42.2a | 74.2 ± 45.1a |
| ALT (U/L) | 15.3 ± 1.9ab | 14.7 ± 1.5ab | 12.9 ± 2.0b | 17.9 ± 3.2a | 18.0 ± 3.4a |
| TC (mg/dL) | 42.2 ± 5.4d | 101.5 ± 8.8a | 93.4 ± 8.1ab | 94.6 ± 12.3ab | 88.2 ± 11.9c |
| TG (mg/dL) | 27.9 ± 5.5a | 30.9 ± 15.7a | 28.6 ± 6.8a | 27.0 ± 8.2a | 25.0 ± 5.9a |
| HDL-C (mg/dL) | 36.6 ± 4.1b | 79.1 ± 5.4a | 73.8 ± 5.2a | 77.0 ± 9.0a | 75.6 ± 6.8a |
| LDL-C (mg/dL) | 4.7 ± 0.4d | 30.4 ± 4.5a | 25.2 ± 3.0b | 25.6 ± 3.8b | 21.1 ± 3.6c |
| HDL/LDL | 7.6 ± 0.7a | 2.7 ± 0.5c | 2.7 ± 0.3c | 3.0 ± 0.2bc | 3.4 ± 0.3b |
| AI (TC/HDL-C) | 1.2 ± 0.1a | 1.3 ± 0.1b | 1.3 ± 0.1b | 1.3 ± 0.1b | 1.2 ± 0.1a |
Data are expressed as mean ± SD (n = 7–8 mice/group). The statistical significance of differences among the five groups were analyzed by one-way ANOVA and Duncan’s multiple range tests. The values with different letters (a–d) are significantly different (p < 0.05) between each group. AI = atherogenic index.