Table 2.
Well | Group | Luciferase Activity (% of control) | Cell Viability (% of control) | Selectivity Indexa |
---|---|---|---|---|
– | Control | 100 | 100 | 1.00 |
A3 | Lapachone | 2 | 11 | 0.18 |
A10 | Idebenone | 55 | 64 | 0.86 |
A12 | HBED | 58 | 98 | 0.59 |
B3 | Hinokitiol | 31 | 83 | 0.37 |
B8 | U83836E | 30 | 59 | 0.51 |
B10 | GERI-BP002A | 16 | 47 | 0.34 |
C4 | CDC | 35 | 90 | 0.39 |
C9 | Gossypol | 19 | 48 | 0.40 |
F7 | Ciclopirox olamine | 61 | 79 | 0.77 |
The Selectivity Index was calculated by diving luciferase activity by cell viability.