Table 1:
Baseline characteristics
| Variable | HA group (n = 75) | Control group (n = 55) | P-Value |
|---|---|---|---|
| Demographics | |||
| Age (years) | 60.7 ± 16.5 | 60.8 ± 13.5 | 0.99 |
| Gender, male | 38 (50.1) | 32 (58.2) | 0.47 |
| Systemic hypertension | 47 (62.7) | 35 (63.6) | 1.00 |
| Coronary artery disease | 25 (33.3) | 13 (23.6) | 0.24 |
| COPD | 12 (16.0) | 10 (18.2) | 0.81 |
| Pulmonary hypertension | 4 (5.3) | 3 (5.5) | 1.00 |
| Dialysis dependent | 6 (8.0) | 5 (9.1) | 1.00 |
| Liver cirrhosis | 3 (4.0) | 2 (3.6) | 1.00 |
| Peripheral vascular disease | 6 (8.0) | 9 (16.3) | 0.17 |
| Atrial fibrillation | 26 (34.7) | 12 (21.8) | 0.12 |
| IV drug abuse | 10 (13.3) | 12 (21.8) | 0.24 |
| Re-operation | 19 (25.2) | 15 (27.2) | 0.84 |
| LV ejection fraction | 52.0 ± 10.7 | 55.2 ± 6.7 | 0.32 |
| History of stroke | 28 (37.3) | 18 (32.7) | 0.71 |
| Fever (≥38.5°C) | 57 (76.0) | 45 (81.8) | 0.51 |
| EuroSCORE II (%) | 11.9 ± 15.2 | 12.0 ± 11.5 | 0.49 |
| SOFA score, preoperative | 1 (0–3) | 2 (0–5) | 0.38 |
| Leucocytes (nl) | 12.3 ± 5.7 | 10.0 ± 4.6 | 0.005 |
| CRP (mg/dl) | 10.3 ± 8.3 | 8.7 ± 7.4 | 0.13 |
| Clinical status | |||
| Intubated | 9 (12.0) | 8 (14.5) | 0.79 |
| Vasopressor need | 9 (12.0) | 7 (12.7) | 1.000 |
| Staphylococcus species | |||
| MSSA | 69 (92.0) | 52 (94.5) | 0.73 |
| MRSA | 6 (8.0) | 3 (5.5) | 0.73 |
| Affected valves | |||
| MV | 28 (37.3) | 25 (45.5) | 0.37 |
| AV | 27 (36.0) | 23 (41.8) | 0.58 |
| MVP | 6 (8.0) | 2 (3.6) | 0.46 |
| AVP | 18 (24.0) | 10 (18.2) | 0.52 |
| TV | 3 (4.0) | 8 (14.5) | 0.05 |
| Multiple valves | 7 (13.3) | 8 (14.5) | 0.41 |
| Total number of valves | 82 | 68 | |
Data are presented as mean ± SD or number (%). SOFA score is presented as median and IQR.
AV: aortic valve; AVP: aortic valve prosthesis; COPD: chronic obstructive pulmonary disease; EuroSCORE: European System for Cardiac Operative Risk Evaluation; HA: haemoadsorption; IQR: interquartile range; IV: intravenous; MRSA: methicillin-resistant Staphylococcus aureus; MSSA: methicillin-susceptible Staphylococcus aureus; MV: mitral valve; MVP: mitral valve prosthesis; SD: standard deviation; SOFA: Sequential Organ Failure Assessment; TV: tricuspid valve; LV: left ventricular; CRP: C-reactive protein.