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. 2023 Feb 15;9(7):eabq1141. doi: 10.1126/sciadv.abq1141

Fig. 2. The cross-talk among microglia, astrocytes, and neurons.

Fig. 2.

The cross-talk between microglia and astrocytes includes neurotransmitters, ligand-receptor binding, soluble mediators, transcriptional regulatory factors, and EVs. EVs carrying miRNAs and α-synuclein can be transported among microglia, astrocytes, and neurons. The neuroinflammatory signals and corresponding mechanisms that lead to neurotoxicity have been shown.