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. 2022 Aug 4;1(8):e0000073. doi: 10.1371/journal.pdig.0000073

Table 2. Prevalence Rate of Diagnoses by Class*.

Diagnostic Cluster Class 1 Class 2 Class 3 Class 4 Class 5 Class 6 Class 7 Class 8
Allergy
1-Asthma w/o Status Asthmaticus 4.58% 6.73% 3.00% 50.20% 4.86% 4.69% 2.96% 4.58%
2-Allergic Rhinitis 9.63% 11.89% 0.63% 31.06% 4.20% 3.47% 2.39% 7.15%
2-Asthma w/o Status Asthmaticus 6.08% 0.03% 2.84% 98.37% 0.27% 2.16% 3.53% 5.98%
Ear Nose Throat
1-Deafness hearing loss 10.92% 0.99% 2.76% 2.09% 4.46% 2.82% 20.10% 0.17%
1-Chronic pharyngitis and tonsillitis 33.05% 0.29% 0.16% 0.93% 0.79% 0.56% 0.62% 0.07%
1-ENT Disorders other 7.53% 0.40% 0.87% 0.81% 1.32% 0.94% 2.29% 0.17%
2-Chronic pharyngitis and tonsillitis 45.51% 0.27% 0.16% 0.26% 0.00% 0.19% 0.10% 0.34%
3-Chronic pharyngitis and tonsillitis 33.99% 0.32% 0.39% 0.67% 0.06% 0.38% 0.62% 0.48%
Gastrointestinal/Hepatic
1-Constipation 0.73% 1.82% 1.34% 1.63% 0.17% 47.07% 1.87% 1.81%
1-Gasteroenteritis 0.60% 1.84% 0.63% 0.73% 0.12% 1.97% 1.30% 22.56%
2-Constipation 1.63% 1.68% 1.58% 1.88% 0.00% 61.76% 4.31% 1.98%
2-Gastroesophageal reflux 3.17% 0.61% 3.55% 3.18% 1.15% 8.82% 4.21% 1.71%
General Signs and Symptoms
1-Fever 1.28% 1.63% 2.29% 2.42% 0.24% 1.78% 0.31% 30.02%
1-Nausea vomiting 0.34% 0.00% 0.71% 0.42% 0.00% 1.88% 0.36% 20.00%
Genito-Urinary
1-Urinary Symptoms 1.50% 1.34% 0.39% 1.74% 2.15% 18.58% 0.68% 0.51%
2-Urinary Symptoms 1.28% 1.66% 0.39% 1.16% 2.20% 17.60% 0.36% 1.71%
Neurologic
1-Headaches 0.43% 0.11% 0.39% 1.09% 0.09% 0.23% 0.57% 28.10%
1-Seizure Disorder 0.47% 0.16% 62.32% 0.22% 0.10% 0.80% 0.57% 0.96%
1-Sleep Problems 21.79% 0.24% 0.87% 0.20% 0.23% 0.38% 1.77% 0.24%
1-Autism Spectrum Disorder 0.09% 0.11% 3.16% 0.20% 0.02% 0.23% 26.81% 0.03%
2-Neurologic signs and symptoms 1.84% 0.61% 10.19% 0.59% 1.54% 1.50% 11.12% 2.19%
2-Headaches 1.11% 0.96% 2.05% 0.76% 0.40% 0.28% 1.14% 21.81%
2-Seizure Disorder 0.68% 0.11% 79.15% 0.08% 0.03% 0.23% 1.35% 0.82%
2-Sleep Problems 22.35% 0.29% 0.95% 0.40% 0.31% 0.80% 5.09% 1.57%
2-Developmental disorder 3.42% 2.30% 17.69% 1.95% 2.37% 3.00% 49.82% 2.29%
2-Autism Spectrum Disorder 0.47% 0.05% 4.82% 0.61% 0.01% 0.84% 47.12% 0.38%
3-Seizure Disorder 0.47% 0.27% 46.84% 0.16% 0.07% 0.19% 0.78% 0.10%
3-Sleep Problems 17.81% 0.48% 0.55% 0.40% 0.07% 0.00% 2.08% 0.55%
3-Developmental disorder 2.31% 1.15% 10.82% 0.70% 1.15% 1.13% 36.21% 1.20%
3-Autism Spectrum Disorder 0.39% 0.21% 2.29% 0.09% 0.00% 0.47% 29.87% 0.27%
Respiratory
1-Respiratory signs and symptoms 11.90% 2.35% 1.26% 4.72% 1.85% 1.50% 0.88% 1.33%
1-Sleep Apnea 23.54% 0.29% 1.18% 0.84% 0.43% 0.75% 0.42% 0.00%
2-Respiratory signs and symptoms 12.37% 4.25% 1.34% 4.33% 1.68% 1.36% 1.25% 2.80%
2-Sleep Apnea 26.50% 0.00% 0.79% 0.99% 0.03% 0.61% 0.36% 0.44%
3-Sleep Apnea 19.82% 0.16% 0.87% 0.40% 0.03% 0.33% 0.99% 0.55%
Skin
1-Dermatitis and eczema 1.54% 54.21% 0.32% 9.28% 0.42% 1.41% 2.13% 0.58%
2- Dermatitis and eczema 2.40% 60.65% 1.66% 13.68% 0.08% 0.89% 2.86% 3.04%

* Highlighted prevalence rates are those greater than or equal to 10%.