Table 2. Performance metric comparison of models built upon the trivial feature set and a single biomarker (Without EHR), and the EHR baseline feature set and a single biomarker (With EHR).

	Without EHR		With EHR
Biomarker	AUROC	AUPRC	AUROC	AUPRC
hDC	0.78 (0.68, 0.88)	0.34 (0.23, 0.48)	0.78 (0.70, 0.86)	0.38 (0.31, 0.45)
SDD	0.81 (0.71, 0.90)	0.44 (0.24, 0.66)	0.81 (0.75, 0.89)	0.49 (0.35, 0.66)
HighDrusenVol	0.81 (0.72, 0.91)	0.49 (0.30, 0.70)	0.82 (0.77, 0.90)	0.52 (0.40, 0.68)
RPD	0.80 (0.70, 0.89)	0.43 (0.29, 0.59)	0.79 (0.72, 0.87)	0.46 (0.39, 0.58)
HRF	0.81 (0.73, 0.90)	0.48 (0.26, 0.69)	0.82 (0.78, 0.91)	0.52 (0.38, 0.68)