Table 1.

Univariate and multivariate Cox regression analysis in MDS patients.

Variables	GSE114922 dataset				JNU-SMU dataset
	Univariate Cox		Multivariate Cox		Univariate Cox		Multivariate Cox
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Gender
Female	Reference		Reference		Reference		Reference
Male	2.88 (1.11, 7.48)	0.030	2.59 (0.95, 7.05)	0.063	3.39 (1.10, 10.48)	0.034	10.10 (2.08, 49.08)	0.004
Age
≤60	Reference		Reference		Reference		Reference
>60	1.33 (0.44, 4.00)	0.611	1.60 (0.48, 5.34)	0.45	0.99 (0.40, 2.47)	0.990	0.97 (0.34, 2.73)	0.951
Risk stratification
Low risk	Reference		Reference		Reference		Reference
Intermediate risk	3.60 (1.30, 9.98)	0.014	0.77 (0.21, 2.87)	0.694	2.78 (0.25, 31.30)	0.404	4.93 (0.27, 90.73)	0.283
High risk	4.57 (1.50, 14.01)	0.008	2.11 (0.56, 8.01)	0.272	2.94 (0.39, 22.24)	0.296	4.40 (0.35, 55.51)	0.252
Risk stratification (estimated by total points)
Low risk	Reference		Reference		Reference		Reference
Intermediate risk	3.90 (1.23, 12.35)	0.021	5.75 (1.28, 25.84)	0.023	1.44 (0.33, 6.39)	0.630	1.32 (0.20, 8.60)	0.770
High risk	12.47 (3.93, 35.56)	<0.001	10.83 (2.87, 40.93)	<0.001	5.01 (1.60, 15.68)	0.006	20.21 (3.90, >100)	<0.001