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Enriched environment reduced the expression of the inflammatory cytokines. (a) Quantitative analysis of TNF-α mRNA levels in the peri-infarct cortex. (b) Quantitative analysis of IL-1β mRNA levels in the peri-infarct cortex. (c) Quantitative analysis of IL-6 mRNA levels in the peri-infarct cortex. n = 3. Data are expressed as mean ± SD. ∗∗∗p < 0.001 vs. SEE group; #p < 0.05, ##p < 0.01, and ###p < 0.001 vs. IEE group.
