Table 5.
Vaccine side effects at 8 weeks from initial dose
| Ocrelizumab | Natalizumab | Fumarate | Interferon beta | |
|---|---|---|---|---|
| All side effects, n (%) | 15 (93.8) | 9 (75.0) | 10 (90.9) | 6 (100.0) |
| Injection site pain | 12 (75.0) | 7 (58.3) | 8 (72.7) | 5 (83.3) |
| Fatigue | 14 (87.5) | 7 (58.3) | 6 (54.5) | 4 (66.7) |
| Headache | 9 (56.3) | 5 (41.7) | 3 (27.3) | 0 (0.0) |
| Myalgia* | 11 (68.8) | 2 (16.7) | 6 (54.5) | 2 (33.3) |
| Arthralgia | 7 (43.8) | 2 (16.7) | 2 (18.2) | 0 (0.0) |
| Fever | 7 (43.8) | 3 (25.0) | 1 (9.1) | 0 (0.0) |
| Chills | 8 (50.0) | 2 (16.7) | 4 (36.4) | 2 (33.3) |
Comparisons were made using one-way analysis of variance with Tukey’s correction for multiple comparisons
*Statistical significance of p < 0.05