Extended Data Fig. 8. KineTACs mediate uptake of extracellular VEGF.
a, Representative flow cytometry showing levels of VEGF-647 cell surface labeling after incubation with HeLa cells for 1 hr at 4 °C and normal versene lift. b, Representative flow cytometry showing reduction of VEGF-647 cell surface labeling after incubation with HeLa cells for 1 hr at 4 °C and lift with 0.25% trypsin-EDTA (trypsin lift). c, Trend of VEGF uptake as calculated by flow cytometry to CXCR7 transcript levels. N = 3 biologically independent experiments. Data are represented as mean values and error bars represent the standard deviation of biological replicates. Linear regression analysis using GraphPad Prism was used to calculate the coefficient of determination (R2) to determine trend. Data are representative of two biological replicates.