Table 1.

Subject demographics.

Characteristic	Metformin-treated subjects (n=14)	Untreated control subject (n=1)
Age (yr)
median	70.5	75
range (min, max)	62, 80	--
Sex
male, n (%)	5 (36)	1 (100)
female, n (%)	9 (64)	--
Body weight
median	87.5	97.2
range (min, max)	56.2, 117.5	--
Body-mass index
median	29.7	29.9
range (min, max)	22.7, 46.6	--
History of T2DM, n (%)	13 (93)	0 (0)
Subject taking metformin at time of study entry, n (%)	13 (93)	0 (0)
Subjects enrolled	19	1
Subjects evaluable	14	1
Subjects non-evaluable	5	--
Reason for non-evaluability:
withdrew due to adverse events*	1	--
did not complete study treatment	2	--
did not complete drug diary	2	--

^*One non-T2DM subject withdrew due to self-reported nausea and diarrhea that the subject attributed to study-prescribed metformin.