Table 2.

Univariable Cox-regression analyses for survival

	Univariable-PFS			Univariable-DSS			Univariable-OS
	HR	CI [95%]	p value	HR	CI [95%]	p value	HR	CI [95%]	p value
Histopathological tumor characteristics
TNM-tumor stage	1.48	0.89–2.47	0.134	2.45	1.60–3.74	< 0.001	2.21	1.56–3.15	< 0.001
FIGO stage	1.87	1.34–2.61	< 0.001	2.89	2.00–4.19	< 0.001	2.25	1.69–2.99	< 0.001
Histological subtype	0.45	0.18–1.12	0.087	0.23	0.09–0.60	0.002	0.34	0.16–0.73	0.006
Histological grading	1.93	1.19–3.12	0.008	3.12	1.66–5.90	< 0.001	2.26	1.44–3.55	< 0.001
Postoperative residual tumor burden	2.22	1.06–4.65	0.034	3.36	1.93–5.85	< 0.001	2.95	1.71–5.08	< 0.001
Anamnestic life style parameter
Mean age [71 ys]	1.13	0.53–2.41	0.746	1.36	0.55–3.36	0.500	1.42	0.71–2.84	0.325
Smoking status	1.38	0.59–3.21	0.455	0.71	0.13–3.97	0.693	0.80	0.24–2.68	0.719
Physical performance status	1.32	0.45–3.85	0.608	0.51	0.23–1.10	0.087	2.01	0.81–5.00	0.131
Cognitive functioning	0.74	0.10–5.47	0.768	0.49	0.23–1.06	0.071	2.29	0.69–7.60	0.177
Global health status assessment tools
G8 Score	2.29	1.04–5.02	0.040	4.71	1.76–12.59	0.002	3.40	1.67–6.95	0.001
Lee-index	1.50	1.02–2.21	0.041	1.51	0.95–2.41	0.084	1.54	1.07–2.22	0.021
CC-index	1.17	0.68–2.02	0.571	2.23	1.11–4.47	0.024	2.21	1.29–3.78	0.004
ASA PS	1.55	0.78–3.09	0.209	2.05	0.88–4.78	0.098	2.26	1.17–4.37	0.015

Bold values indicate significant results (p < 0.05)

Italic values indicate clinically relevant results (p < 0.1)

PFS progression-free survival, DSS disease-specific survival, OS overall survival, HR hazard ratio, CI confidence interval, TNM-FIGO tumor staging system-international federation of gynecology and obstetrics, G8 Score G8 geriatric screening tool, Lee-Index Lee-Schonberg prognostic index, CCI Charlson comorbidity index, ASA PS American society of anesthesiologists physical status system