Table 4.
Estimated 5-year survival rates by Kaplan–Meier method in relation to preoperative frailty status
| Global health status assessment tools – frailty status classification | n (%) | PFS after 5 years [%], p value | DSS after 5 years [%], p value | OS after 5 years [%], p value |
|---|---|---|---|---|
| G8 geriatric screening tool (G8 Score) | 150 | 0.071 | 0.001 | < 0.001 |
| G8-non-frail | 92 (61.3) | 82.1 | 93.8 | 88.2 |
| G8-frail | 58 (38.7) | 65.4 | 60.8 | 49.7 |
| Lee Schonberg prognostic index (Lee-index) (4-year mortality [%]) | 146 | 0.039 | 0.128 | 0.039 |
| 0 (< 10) | 57 (39.0 | 83.1 | 86.8 | 82.9 |
| 1 (10–< 20) | 28 (19.2) | 85.3 | 94.4 | 78.1 |
| 2 (20–< 30) | 50 (34.2) | 55.9 | 75.8 | 69.0 |
| 3 (> 30) | 11 (7.5) | 66.7 | 57.1 | 42.0 |
| American society of anesthesiologists physical status (ASA PS) | 152 | 0.462 | 0.277 | 0.020 |
| 1 | 4 (2.6) | 75.0 | 100.0 | 75.0 |
| 2 | 59 (38.8) | 81.4 | 91.2 | 91.2 |
| 3 | 87 (57.2) | 71.5 | 76.7 | 64.3 |
| 4 | 2 (1.3) | 0.0 | 0.0 | 0.0 |
| Charlson comorbidity index (CC-Index) (1-year mortality [%]) | 154 | 0.173 | 0.015 | < 0.001 |
| 0 (12%) | 0 (0.0) | 0.0 | 0.0 | 0.0 |
| 1 (26%) | 37 (24.0) | 73.6 | 93.8 | 84.4 |
| 2 (52%) | 73 (47.4) | 79.0 | 89.3 | 87.3 |
| 3 (85%) | 44. (28.6) | 61.8 | 64.6 | 50.4 |
Bold values indicate significant results (p < 0.05)
Italic values indicate clinically relevant results (p < 0.1)
PFS progression-free survival, OS overall survival, DSS disease-specific survival