Table 4.
Comparison of patient- and hospital-related data of all matched patients with a new unplanned wound revision depending on the wound dressing
| Variable | Treatment failures | ||
|---|---|---|---|
| Wound dressing | Total (n = 19) | Epi-VAC (n = 12) | Control group (n = 7) |
| Mean age (years) | 65.7 ± 13.6 | 67.2 ± 10.2 | 63.1 ± 18.7 |
| Body mass index (kg/m2) | 30.4 ± 6.9 | 32.36 ± 6.7 | 26.93 ± 6.1 |
| Male (%) | 63.2 | 50 | 85.7 |
| ASA score | 2.7 | 2.7 | 2.7 |
| Diabetes mellitus (%) | 47.4 | 58.3 | 28.6 |
| Insulin-dependent (%) | 36.8 | 50 | 14.3 |
| Oral antidiabetics (%) | 0 | 0 | 0 |
| Pressure ulcer (%) | 15.8 | 25 | 0 |
| At least one concomitant disease (%) | 89.5 | 100 | 71.4 |
| Nicotine abuse (%) | 21.1 | 16.7 | 28.6 |
| Systemic cortisone therapy (%) | 5.3 | 0 | 14.3 |
| Peripheral arterial disease (PAVD) (%) | 5.3 | 0 | 14.3 |
| Coronary artery disease (CAD) (%) | 15.8 | 16.7 | 14.3 |
| Arterial hypertension (%) | 84.2 | 91.7 | 71.4 |
| COPD (%) | 10.5 | 0 | 28.6 |
| Active cancer (%) | 26.3 | 16.7 | 42.9 |
| Osteoporosis (%) | 21.1 | 25 | 14.3 |
| Renal insufficiency ≥ 3 (%) | 31.6 | 33.3 | 28.6 |
| Anticoagulation (%) | 5.3 | 25 | 14.3 |
| Albumin (g/l) | 28.8 ± 7.23 | 28.47 ± 7.77 | 29.45 ± 6.63 |
| Hemoglobin (mmol/l) | 5.79 ± 1.05 | 5.76 ± 1.03 | 5.84 ± 1.16 |
| C-reactive protein (mg/l) | 161.94 ± 117.18 | 186.66 ± 128.92 | 119.56 ± 86.04 |
| Leukocytes (× 109/l) | 10.95 ± 3.45 | 10.9 ± 4.12 | 11.04 ± 2.13 |
| Number of addressed vertebral bodies (n) | 5.6 ± 3.1 | 5.2 ± 2.7 | 6.4 ± 3.8 |
| Duration of initial surgery (min) | 169.6 ± 65.2 | 152.8 ± 55.5 | 203.2 ± 75 |
| Duration of revision surgery (min) | 63.6 ± 16.1 | 60.4 ± 15.8 | 69 ± 16.5 |
| Time between first and second WR (days) | 11.7 ± 7 | 12 ± 8.1 | 11.3 ± 5.2 |
| Length of hospital stay (days) | 49.9 ± 29.2 | 51 ± 31.6 | 48 ± 26.9 |
| ICU admission (%) | 47.4 | 50 | 42.9 |
| Length of ICU stay (days) | 8.8 ± 17.8 | 11.5 ± 21.9 | 3.3 ± 1.2 |
| Mortality (%) | 10.5 | 8.3 | 14.3 |
| Local antibiotic therapy (%) | 100 | 100 | 100 |
| Germ (%) | 78.9 | 75 | 85.7 |
| S. epidermidis (%) | 21.1 | 16.7 | 28.6 |
| S. aureus (%) | 42.1 | 33.3 | 57.1 |
| Propionibacterium acnes (%) | 0 | 0 | 0 |
| E. faecalis (%) | 10.5 | 16.7 | 0 |
| E. coli (%) | 10.5 | 16.7 | 0 |
| Pseudomonas aeruginosa (%) | 0 | 0 | 0 |
| Another germ (%) | 26.3 | 25 | 28.6 |
| Mixed infections (%) | 26.3 | 25 | 28.6 |
Data indicated as mean or percentage
PAVD peripheral arterial disease, COPD chronic obstructive pulmonary disease, WR wound revision