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. 2022 Feb 18;149(2):811–817. doi: 10.1007/s00432-021-03847-5

Table 3.

Summary of adverse events reported in all R/R FL and DLBCL patients (safety population)

R/R FL
G-atezo-pola
(N = 13)
R/R DLBCL
R-atezo-pola
(N = 21)
Patients with ≥ 1 AE, n (%) 13 (100.0) 17 (81.0)
Grade 3–5 AE, n (%) 8 (62.0) 5 (24.0)
Grade 5 (fatal) AE, n (%) 2 (15.0)a 1 (5.0)b
Serious AE, n (%) 4 (31.0) 2 (10.0)
AE leading to any drug discontinuation, n (%) 2 (15.0)
AE leading to pola dose reduction, n (%) 1 (8.0)c
AE leading to any dose interruption or modification, n (%) 6 (46.0) 3 (14.0)

AE adverse event, atezo atezolizumab, DLBCL diffuse large B-cell lymphoma, FL follicular lymphoma, G obinutuzumab, pola polatuzumab vedotin, R rituximab, R/R relapsed/refractory

aBronchopulmonary aspergillosis (n = 1) and unknown (n = 1)

bPleural effusion (n = 1; a complication of sepsis)

cPeripheral neuropathy (n = 1)