Table 3.
R/R FL G-atezo-pola (N = 13) |
R/R DLBCL R-atezo-pola (N = 21) |
|
---|---|---|
Patients with ≥ 1 AE, n (%) | 13 (100.0) | 17 (81.0) |
Grade 3–5 AE, n (%) | 8 (62.0) | 5 (24.0) |
Grade 5 (fatal) AE, n (%) | 2 (15.0)a | 1 (5.0)b |
Serious AE, n (%) | 4 (31.0) | 2 (10.0) |
AE leading to any drug discontinuation, n (%) | 2 (15.0) | – |
AE leading to pola dose reduction, n (%) | 1 (8.0)c | – |
AE leading to any dose interruption or modification, n (%) | 6 (46.0) | 3 (14.0) |
AE adverse event, atezo atezolizumab, DLBCL diffuse large B-cell lymphoma, FL follicular lymphoma, G obinutuzumab, pola polatuzumab vedotin, R rituximab, R/R relapsed/refractory
aBronchopulmonary aspergillosis (n = 1) and unknown (n = 1)
bPleural effusion (n = 1; a complication of sepsis)
cPeripheral neuropathy (n = 1)