TABLE 1.

Patient demographic and clinical characteristics.

Case number	Sex	Age	ETP-ALL or not	Risk stratification	Prednisone test	CNS involvement	Karyotype	Gene variants	HSCT	Relapsed
1	1	13.4	No	HR	1	No	46, XY, inv(9)(p12q13)c[7]	(–)	No	No
2	1	6.4	Yes	HR	2	No	46, XY[5]	(–)	Yes	No
3	1	1.8	No	HR	2	No	46, XY[11]	(–)	No	No
4	1	10	No	HR	1	No	46, XY[4]	(–)	Yes	No
5	1	5.1	No	IR	1	No	46, XY[3]	SIL/TAL1(+)	No	No
6	1	6.1	No	HR	2	No	46, XY[20]	(–)	No	No
7	2	4.2	No	HR	2	No	46, XX[17]	(–)	No	No
8	1	11.3	No	HR	2	No	46, XY[5]	MLL/AF6(+)	Yes	No
9	1	3.8	No	HR	2	No	46, XY[6]	SIL/TAL1(+), P16(+)	Yes	No
10	1	7.7	No	HR	2	No	46, XY, add(2)(q33)[5]/46, XY[10]	(–)	No	No
11	1	12.2	No	IR	1	No	46, XY[1]	P16(+)	No	No
12	1	12.1	Yes	HR	1	Yes	46, XY[20]	(–)	Yes	Yes
13	1	9.4	No	IR	1	No	46, XY, der(9)(p21;p23)[5]/46, XY[5]	(–)	No	No
14	1	8.9	No	HR	1	No	46, XY, der(9)(q12;q31),del(13) (q13;q31), ?−8,?+12[cp9]/46, XY[11]	NOTCH1	No	No
15	1	12	No	HR	1	No	46, XY, t(11;14)(p15;q11)[5]/46, XY, [5]	NOTCH1, FBXW7	No	No
16	1	7.1	No	HR	1	No	46, XY[20]	(–)	Yes	No
17	1	5.3	No	IR	1	No	46, XY[20]	(–)	No	No
18	1	9.2	No	HR	2	No	46, XY[8]	BRAF, NOTCH1	Yes	No
19	1	13.7	No	HR	1	Yes	46, XY[15]	P16(+)	Yes	No
20	1	2.4	No	IR	1	No	NA	NOTCH1	No	Yes
21	1	7	No	HR	2	No	46, xy[16]	HOX11	Yes	No
22	2	7.3	No	IR	1	No	46, xx, 6p-[6]/46, xx[5]	(–)	No	No
23	1	11.4	No	IR	1	No	46, XY, del(9)(p10)[10]	(–)	No	No
24	2	8.9	No	HR	2	No	46, XX	SIL-TAL1, FBXW7, NOTCH1	Yes	No
25	1	3.2	No	IR	1	No	46, XY	(–)	No	No
26	1	13.5	No	IR	1	Yes	46, XY, t(1:16)(p31:q22), del(9)(p21), del(9)(p21)[4]/46, XY[6]	FBXW7 NOTCH	Yes	No
27	1	13.3	No	HR	3	No	46, XY, del(9)(p21.3)	NOTCH1, FBXW7, PTEN, P16(+)	Yes	No

NA, not available; Sex (1 = male, 2 = female); Prednisone test (1 = GPR, 2 = PPR, and 3 = not evaluated); GPR, good prednisone response; PPR, poor prednisone response; CNS, central nervous system; HR, high risk group; IR, intermediate risk group; HSCT, allogeneic hematopoietic stem cell transplantation; P16(+), P16 deletion.