Table 2.

P-values for group comparisons for clinical and hemodynamic variables at baseline vs. following oral benazepril dosing at 0.125, 0.25, or 0.5 mg/kg in 9 healthy beagle dogs.

Variable	Baseline vs. 0.125 mg/kg	Baseline vs. 0.25 mg/kg	Baseline vs. 0.5 mg/kg	0.125 vs. 0.25 mg/kg	0.25 vs. 0.5 mg/kg	0.125 vs. 0.5 mg/kg
Weight	0.83	0.54	0.54	0.79	0.93	0.89
Heart rate	0.074	0.64	0.011*	0.18	0.034*	0.40
BP	0.010*	0.044*	0.14	0.54	0.57	0.24
LVIDd	0.33	0.27	1.00	0.72	0.19	0.22
LVIDs	0.87	0.40	0.69	0.50	0.66	0.81
LA:Ao	0.42	0.53	0.42	0.16	0.16	1.00
FS	0.57	0.033	0.88	0.11	0.046*	0.68
EDVI	0.16	0.26	0.48	0.67	0.72	0.66
ESVI	0.55	0.21	0.78	0.51	0.13	0.39
EF	0.34	0.83	0.34	0.35	0.22	0.45
E vel	0.22	0.12	0.20	0.73	0.78	0.95
A vel	0.00053*	0.013*	0.0018*	0.23	0.43	0.66
E:A	0.015*	0.10	0.0054*	0.26	0.39	0.73
IVRT	0.034*	0.044*	0.063	0.91	0.86	0.77
E:IVRT	0.024*	0.031*	0.057	0.80	0.96	0.72

Group comparisons were performed using t tests (normally-distributed data) or Wilcoxon rank-sum tests (non-normally distributed data). Significant differences (P-value < 0.05) are designated with bolding and an asterisk (*).

BP blood pressure, LVIDd left ventricular internal diameter in diastole, LVIDs left ventricular internal diameter in systole, LA:Ao a ratio of left atrium to aorta diameter, FS fractional shortening, EDVI end-diastolic volume index, ESVI end-systolic volume index, EF ejection fraction, E vel maximum velocity of early diastolic transmitral inflow, A vel maximum velocity of late diastolic transmitral inflow, E:A ratio of early to late diastolic transmitral inflow, IVRT isovolumic relaxation time, E:IVRT ratio of early diastolic transmitral inflow to IVRT.