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Induction of antigen-induced arthritis (AIA) in rabbits.
| Day | Procedure | OVA (mg/per rabbit) | CFA (ml/per rabbit) | Injection site |
|---|---|---|---|---|
| −28 | Immunization | 10 | 0.5 | SC |
| −21 | Immunization | 10 | 0.5 | SC |
| −14 | Immunization | 10 | 0.5 | SC |
| −7 | IA Injection | 10 | 0.5 | IA |
| 0 | CEL formulation treat | – | – | IA |
