Table 1.
Demographic and clinical characteristics, Univariate and Multivariate analysis of AIS group and healthy control group.
| Characteristics | Healthy control group, n = 107 | AIS group, n = 328 | Univariate and Multivariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|---|---|
| OR (95%CI) | SE | P value | OR (95%CI) | SE | P value | |||
| Age, y | 66.81 ± 10.39 | 68.48 ± 11.14 | 1.01 (1.00–1.03) | 0.009 | 0.173 | / | / | / |
| Men, n(%) | 64(59.81) | 227(69.21) | 1.01(0.93–1.11) | 0.05 | 0.756 | / | / | / |
| BMI(kg/m2) | 24.65 ± 2.97 | 24.18 ± 3.07 | 0.95 (0.88–1.02) | 0.033 | 0.167 | / | / | / |
| Hypertension(%) | 58(54.2) | 231(70.43) | 2.66 (1.69–4.20) | 0.62 | <0.05 | 4.14 (1.84–9.33) | 1.72 | 0.001 |
| CHD(%) | 8(7.48) | 43(13.10) | 1.86 (0.85–4.11) | 0.751 | 0.121 | / | / | / |
| AF(%) | 4(3.74) | 51(15.55) | 4.74 (1.67–13.44) | 2.52 | 0.003 | 5.77 (1.28–26.11) | 4.44 | 0.023 |
| Diabetes mellitus(%) | 22(20.56) | 105(30.01) | 1.06 (0.62–1.83) | 0.29 | 0.812 | / | / | / |
| Family history of cardiovascular and cerebrovascular events(%) | 14(13.08) | 52(15.85) | 1.25 (0.66–2.36) | 0.4 | 0.489 | / | / | / |
| Smoking history (%) | 26(24.30) | 65(19.82) | 1.16 (0.73–1.85) | 0.27 | 0.693 | / | / | / |
| TC, mmol/L | 4.85 ± 1.09 | 3.97 ± 1.05 | 0.45 (0.36–0.58) | 0.05 | <0.05 | 0.04 (0.01–0.16) | 0.02 | <0.05 |
| TG, mmol/L | 1.65 ± 0.72 | 1.55 ± 1.07 | 0.91 (0.74–1.12) | 0.09 | 0.373 | / | / | / |
| HDL, mmol/L | 1.46 ± 0.41 | 1.13 ± 0.53 | 0.30 (0.39–0.50) | 0.08 | <0.05 | / | / | / |
| LDL, mmol/L | 2.64 ± 0.92 | 2.44 ± 0.88 | 0.78 (0.62–1.00) | 0.09 | 0.049 | 6.55 (1.09–39.58) | 6.01 | 0.04 |
| FSG, mmol/L | 5.57 ± 1.22 | 6.70 ± 3.20 | 1.24 (1.10–1.42) | 0.08 | 0.001 | / | / | / |
| HbA1c | 5.67 ± 1.11 | 6.75 ± 1.69 | 2.04 (1.56–2.67) | 0.28 | <0.05 | 2.28 (1.40–3.71) | 0.56 | 0.001 |
| XO, ng/mL | 0.78 ± 0.51 | 1.76 ± 0.87 | 6.29 (4.13–9.56) | 1.34 | <0.05 | 8.68 (4.62–14.33) | 2.8 | <0.05 |
BMI, Body mass index; CHD, Coronary heart disease; AF, Atrial fibrillation; TC, Total cholesterol; TG, Triglyceride; HDL, High-density lipoprotein; LDL, Low-density lipoprotein; FSG, Fasting blood glucose; HbA1c, Glycosylated hemoglobin; XO, Xanthine oxidase.