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. 2022 Dec 7;29(4):754–763. doi: 10.1158/1078-0432.CCR-22-1983

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©2022 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 4. Tremelimumab exposure-efficacy analysis stratified by Cmin1 for (A) PFS and (B) OS (exposure-response analysis population); N = 216. Median Cmin1 was 12 μg/mL. N, number of patients included in the analysis. — Tremelimumab exposure-efficacy analysis stratified by C_min1 for (A) PFS and (B) OS (exposure-response analysis population); N = 216. Median C_min1 was 12 μg/mL. CI, confidence interval; Cmin1, minimum tremelimumab concentration at day 28; HR, hazard ratio; N, number of patients included in the analysis; OS, overall survival; PFS, progression-free survival.