Fig. 4.

AAV_SOF normalizes ovary morphology. Panels show the representative histology of ovaries from (A) WT mice, (B) Scarb1^−/− mice, (C) Scarb1^−/− receiving AAV_SOF. Primordial follicle, PF (black); primary follicle, P1F (blue); secondary follicle, S2F (green); corpus luteum, CL (red). Notably, the corpus luteum, which is not formed in ovaries from Scarb1^−/− mice, is restored by AAV_SOF. The ages of the mice studied ranged from 12 to 20 weeks and there was no meaningful within-group difference among the ovaries.