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. 2022 Dec 31;64(2):100327. doi: 10.1016/j.jlr.2022.100327

Fig. 5.

Fig. 5

Lipid compositions of plasma (A–C) and HDL (D–F) from WT and Scarb1-/- mice. As labeled, the mice were grouped as WT, Scarb1−/− untreated, Scarb1−/− treated with AAVSOF and fertile, and Scarb1-/- treated with AAVSOF and infertile. (A) Plasma lipid compositions, (B) Plasma-mol% FC, (C) Plasma-FC/TC weight ratios, (D) HDL lipid compositions, (E) HDL-mol% FC, (F) HDL-FC/TC weight ratios. Mol% plasma FC = 100 × molesFC/(molesFC + molesPL). The respective mean age ± SD and age ranges (weeks) were as follows: WT—20.4 ± 2.5 and 16–23; Scarb1−/−—19.5 ± 3.7 and 14–23; AAVSOF Scarb1−/− Fertile—39.5 ± 4.5 and 27–43; AAVSOF Scarb1−/− Infertile—42.8 ± 1.4 and 41–45. The respective number of mice per group were 12, 11, 12, and 13. FC, free cholesterol; TC, total cholesterol.