TABLE 7.
Area under the curve (AUCs) at baseline (week 0) and at the end of the intervention periods (week 3) expressed as median and IQR (n = 31).
| Parameter | Week | Roasted oat flakes (A) | Roasted barley flakes (B) | Traditional oat flakes (C) | Traditional barley flakes (D) | Control | P treatment effect# | ||||||||||
| Median/IQR | p * | ♢ | Median/IQR | p * | ♢ | Median/IQR | p * | ♢ | Median/IQR | p * | ♢ | Median/IQR | p * | ♢ | |||
| AUC glucose [(mmol/l) × min] | 0 | 1,024.5/184.5 | 1,035.0/182.3 | 1,045.5/205.9 | 1,019.3/233.3 | 1,005.0/191.3 | n.s. | ||||||||||
| 3 | 1,020.0/178.5 | n.s. | 1,004.3/116.6 | n.s. | 1,005.0/156.4 | ≤0.05 | 1,044.3/207.4 | n.s. | 1,021.5/226.5 | n.s. | |||||||
| Change from baseline [%] | −1.3/8.9 | a | −0.3/17.0 | a | −4.9/13.3 | a | 1.6/11.2 | a | −1.6/11.4 | a | |||||||
| AUC insulin [(mmol/l) × min] | 0 | 4,746.8/4,257.8 | 3,647.3/3,013.5 | 4,470.0/4,161.4 | 3,273.8/3,056.6 | 4,746.8/3,624.0 | n.s. | ||||||||||
| 3 | 4,352.3/3,865.5 | n.s. | 3,916.5/3,157.1 | n.s. | 4,068.0/3,190.9 | n.s. | 3,478.5/3,202.5 | n.s. | 4,011.0/3,838.1 | n.s. | |||||||
| Change from baseline [%] | 0.2/38.7 | a | 2.7/26.4 | a | −9.4/23.4 | a | 1.9/24.7 | a | −1.6/40.0 | a | |||||||
| AUC TC [(mmol/l) × min] | 0 | 1,029.7/193.2 | 1,070.5/191.3 | 1,004.9/129.8 | 1,011.3/197.6 | 1,046.9/208.2 | ≤0.001 | ||||||||||
| 3 | 1,005.9/175.7 | ≤0.01 | 1,015.8/188.1 | ≤0.001 | 1,010.8/143.3 | ≤0.01 | 988.8/201.2 | ≤0.01 | 1,026.8/162.7 | ≤0.1 | |||||||
| Change from baseline [%] | −6.7/8.7 | a | −3.6/6.7 | a | −3.4/11.5 | a | −5.5/9.4 | a | 3.6/10.4 | b | |||||||
| AUC triglycerides [(mmol/l) × min] | 0 | 198.3/108.5 | 195.1/134.6 | 235.3/110.2 | 214.5/97.8 | 218.9/119.7 | n.s. | ||||||||||
| 3 | 213.8/124.7 | n.s. | 216.0/98.1 | n.s. | 230.0/125.0 | n.s. | 222.2/115.1 | n.s. | 245.6/124.9 | n.s. | |||||||
| Change from baseline [%] | 2.3/31.8 | a | 7.8/45.1 | a | 2.8/45.4 | a | 3.4/19.3 | a | 6.3/34.7 | a | |||||||
| AUC LDL cholesterol [(mmol/l) × min] | 0 | 665.4/191.0 | 698.0/234.7 | 652.7/176.9 | 656.8/196.3 | 680.8/185.1 | ≤0.05 | ||||||||||
| 3 | 628.1/154.7 | ≤0.001 | 623.1/197.2 | ≤0.05 | 644.5/168.3 | ≤0.01 | 647.0/187.1 | ≤0.01 | 652.3/201.2 | n.s. | |||||||
| Change from baseline [%] | −9.6/13.1 | a | −3.4/15.0 | a, b | −4.7/15.0 | a | −7.0/9.6 | a, b | 2.5/14.5 | b | |||||||
| AUC HDL cholesterol [(mmol/l) × min] | 0 | 266.0/102.5 | 254.3/104.4 | 264.0/110.1 | 256.6/112.8 | 247.8/99.4 | ≤0.001 | ||||||||||
| 3 | 249.3/113.7 | ≤0.1 | 248.6/90.6 | ≤0.001 | 273.1/116.6 | ≤0.1 | 245.1/89.7 | ≤0.1 | 252.5/111.6 | ≤0.05 | |||||||
| Change from baseline [%] | −2.5/10.6 | a, b | −5.9/11.8 | a | −3.2/8.2 | a, b | −2.8/10.0 | a, b | 4.0/12.6 | b | |||||||
*Significance of comparing week 0 and week 3 within the same group as determined by Wilcoxon signed-rank test.
♢Interventions without a common letter are significantly different by Tukey’s test, p ≤ 0.05.
#Significance of main effect of treatment by mixed model with random intercept. AUC, area under the curve; HDL, high-density lipoprotein; LDL, low-density lipoprotein; n.s., not significant (p > 0.05); TC, total cholesterol.