Figure 1.
Severe and recovered COVID-19 patients have greater frequencies of CD62L+ T cells. The frequencies of CD4+ and CD8+ T cells (viable, CD14-, CD56-, CD19-, CD3+, CD4+ or CD8+ cells) expressing CD62L in non-severe and severe COVID-19 patients, recovered COVID-19 patients, and healthy controls were assessed by flow cytometry. (A) CD62L+ CD4+ T cells and representative flow cytometry plots. Each plot represents a different patient; percentages of CD4+ CD62L+ CD27+ cells (B), CD4+ CD62L+ CTLA-4+ cells (C), CD4+ CD62L+ PD-1+ cells (D), CD8+ CD62L+ cells and representative flow plots (E), and CD8+ CD62L+ CD27+ cells (F) within the total CD4+ T cell (A-D) and CD8+ T cell (E, F) populations; *p<0.05, **p<0.01 one-way ANOVA with multiple comparisons correction. Data are graphed as percentages of the total CD4+ or CD8+ T cell population.